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供應(yīng) AZD-8330(ARRY-424704) /869357-68-6  |
規(guī) 格: |
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價 格: |
1/ |
數(shù) 量: |
1 |
交貨地: |
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發(fā)布時間: |
2016-07-28 |
有效期: |
255天 |
備 注: |
AZD8330 is an orally active, selective MEK inhibitor with an IC50 of 7 nM.
AZD8330 potently and strongly inhibits MEK 1/2. AZD8330 has no inhibitory activity against over 200 other kinases including at concentrations up to 10 μM. AZD8330 demonstrates sub-nanomolar potency in mechanistic (pERK) and low to sub-nanomolar potency in functional (proliferation) assays in MEK 1/2 inhibitor sensitive cell lines.
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結(jié)構(gòu)式: |
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